City missed the chance to close the gap at the top of the Barclays Premier League after suffering a narrow defeat at Spurs.
Harry Kane scored the only goal of the game in the first-half when Tottenham pounced on a mix-up at the back to finish past Ederson.
Riyad Mahrez came closest to an equaliser just before half-time with a volley that smacked off the woodwork.
Spurs were reduced to 10 men in the dying minutes when Cristian Romero was sent off but the home side survived.
